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Abstract:

Recent decades exhibit a tendency to the rise of gynecological malignant tumors occurence, which makes a substantial contribution to women mortality rate. Wide application of surgery makes it crucial to specify the nature of a lesion, its location, and the degree of the neighboring tissue and lymphatic nodes involvement. Early recognition, accurate staging and localization, and timely recurrent tumor detection are the primary tasks of radiodiagnostics. Computed tomography and magnetic resonance imaging show good results in gynecological tumors detection.

Clinical application of new radiological methods develops the diagnostic accuracy, decreases the number of errors and improves the survival rate. The basic radiological diagnostic procedures and the possibilities of their clinical application are discussed in the article in a form of the survey of literature.

 

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Abstract:

Introduction. 199Tl-chloride scintigraphy is used to visualize tumors. In addition to typical imaging of the musculoskeletal malignancy, unusually types of malignant tumor visualization were revealed by studies of diagnostic potentialities of 199Tl-chloride scintigraphy, analogue of 201Tl-chloride scintigraphy.

Aim. Was to study features of malignant tumor visualization of the musculoskeletal system with the help of 199Tl-chloride scintigraphy.

Materials and methods. 85 patients with diseases of musculoskeletal system underwent 199Tl-chloride scintigraphy. 107 localizations of malignant tumors (n=57) and benign lesion (n=50) were investigated. During the research in 107 patients malignant tumors were detected, 50 patients had bening tumors.

Results. Malignant tumors were visualized in 98.1%. Three types of malignant tumors' visualization were obtained - positive (82.4%) and rare negative (7.8%) and mixed (9.8%). Types of visualization were associated with tumor histological types, blood-flow, metabolism, and pharmacodynamic features of 199Tl-chloride. Negative and mixed visual types were high specific for primary and recurrent malignant tumors, but no metastasis.

Conclusion. Accounting to negative and mixed visual types - 199Tl-chloride scintigraphy sensitivity increased to 98.1% without decreasing of specificity in detection of malignant tumors of musculoskeletal system.

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